A biological topic of great interest is to understand the mechanisms of aging. The nervous system is known to clearly affect aging, especially the hypothalamus, but the mechanism by which it occurs is presently unknown.


Cells that had been genetically engineered to survive in the aging-related enviroment


Now, a recent article pubilshed in NATURE has evaluated this topic, and shown that the speed of aging is partially controlled by hypothalamic stem cells and the release of exosomal microRNA in the cerebrospinal fluid. Conversely, aging retardation and lifespan extension were achieved in mid-aged mice that were locally implanted with healthy hypothalamic stem/progenitor cells that had been genetically engineered to survive in the aging-related enviroment. These new aging controls could have clear implications in transhumanist schools of thought, which are being promoted lately.

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