CRISPR-Cas9, the gene editing tool, might cause cancer. Why do Crispr presents so many difficulties on humans?

Editing cells’ genomes with CRISPR-Cas9  might increase the risk that the altered cells, intended to treat disease, will trigger cancer, two studies published on Monday warn [2018, Jun 11]— a potential game-changer for the companies developing CRISPR-based therapies. (Begley,...

Duchenne muscular dystrophy could be treated with genome editing using CRISPR/Cas9 technique

Genome editing using  CRISPR/Cas9 is a promising possibility for correcting diseases due to genetic mutations (see HERE ), such as Duchenne muscular dystrophy – lethal degeneration of cardiac and skeletal muscle caused by different genetic mutations (see more HERE), which...

CRISPR-Cas9 brings the possibility of performing pig-to-human xenotransplantation closer

Use chimeric animals as organ incubators, a hopeful means to resolve increasing organ shortage The shortage of human organs and tissues for transplantation represents one of the most critical unmet medical needs today. To address this problem, xenotransplantation, i.e. the use of...

CRISPR: the genome editing tool reveals the keys to embryonic development

At the beginning of 2016, the United Kingdom Human Fertilisation and Embryology Authority (HFEA) announced that it had approved a request from the Francis Crick Institute to use the new genome-editing techniques in human embryos for the first time in the country. The aim was to...

CRISPR. Viable human embryos genetically edited in the USA. Technique and ethical controversies

Numerous complications could go unnoticed in this study On 26th July, the journal MIT Technology Review  announced that the CRISPR technique (see HERE) had been applied in human embryos for the first time in the United States, in a study led by embryologist Shoukhrat Mitalipov of...

CRISPR diagnoisis tool. A new biomedical breakthrough from genome editing to disease diagnosis

CRISPR techniques are gaining traction in another realm of medical technology. CRISPR diagnosis tool It has recently been announced that the CRISPR tool, used up to now in the field of genome editing, can be used in another field, namely in diagnosis, combining it with the enzyme...

CRISPR used in viable human embryos and germline genetic modification. An ethical approach

From an ethical point of view, the use and destruction of human embryos, members of our species and worthy of full dignity is completely unacceptable and, it should be noted,  these experiments involve genetic modification of the germline, the safety of which is still far from...

CRISPR used for the first time in humans

A team led by oncologist Lu Youou at Sichuan University in China has become the first to use the revolutionary CRISPR technique on a patient with aggressive lung cancer as part of a clinical trial at the West China Hospital, according to an article published in Nature. The use of...

CRISPR veterinary (genome editing) to attempt to halt a serious porcine disease

CRISPR veterinary applied to prevent the spread of a serious swine disease.  One of the worst nightmares for any pig farmer is to have a herd infected with porcine reproductive and respiratory syndrome virus (PRRSV). Having emerged in the 1980s, the syndrome now affects these...

Genome editing. First clinical trial using the CRISPR technique authorised in humans

If there is one technique on which biomedicine has pinned its hopes, it is CRISPR, a genome editing technology that simplifies and facilitates the changes to be made in the genome (read our ethical opinion HERE) . This sort of genetic “cut and paste” has just received...