Pulmonary organoids produced from human iPS cells in three dimensions (3D)

Lung organoids have been produced from human pluripotent stem (iPS) cells that contain various components of lung tissue, and even airways and alveolar structures (see HERE). Recapitulation of lung development from human pluripotent stem cells (hPSCs) in three dimensions (3D)...

Ten years since the discovery of iPS cells. The current state of their clinical application

  Rev Clin Esp. 2017 Jan – Feb;217(1):30-34. doi: 10.1016/j.rce.2016.08.003. Epub 2016 Oct 5. Justo Aznar Ph.D. MD Julio Tudela Pharm Ph.D. Institute of Life Science – Bioethics Observatory Catholic University of Valencia – Spain iPS cells current clinical...

Stem cell research. The two sides of the coin

Science facing market The “heads” of stem cell research Stem cells today represent a great hope for the future of regenerative medicine due to their ability to differentiate into cell lines of almost any tissue, making them a promising therapeutic option for many...

Serotonin produced from neurons obtained with iPS and embryonic stem cells

Serotonin is implicated in functions as important as humour, sadness, feelings of aggression, anxiety and sleep disturbances, among others. A deficiency in serotonin release has been related with schizophrenia, depression, bipolar disorder, obsessive-compulsive disorders, chronic...

What is the current clinical usefulness of stem cell treatments, embryonic and iPS cells?

Human adult stem cells (iPS) have been found to be the most clinically useful human cells for therapeutic purposes Pluripotent cells (iPS) are defined as those from which cells of different tissue types can be obtained. These can be obtained either from preimplantation human...

Stem cell therapy by cardiomyocytes derivied from embryonic cells

Objectives ethical difficulties Stem cell therapy: Functional cardiomyocytes can be derived from pluripotent stem cells, and thus be used to repair damaged hearts. There are numerous experiments in this field. These cells have been specially derived from human embryos (embryonic...
Posted On 25 Mar 2015
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New advances and challenges in the production of human-animal chimeras

They had overcome the obstacle of using human embryonic stem cells, but that even so, a ethical difficulty remained with the producing organs formed almost entirely of human cells in experimental animals. It seems a little excessive that, in less than two months, we have...

Parthenogenesis. A new possibility for regenerative medicine and a new bioethical dilemma

Parthenogenesis have allowed pluripotent stem cells to be obtained from oocytes (eggs) which have been stimulated to divide without having been fertilised by sperm. Can individuals be obtained from parthenogenesis? What is a partenote? Introduction A recent sentence from the...

Scientists create a “mini-brain”

According to an article published in Nature (501; 373-379, 2013), a group of Austrian researchers has managed to create a cerebral organ derived from human pluripotent stem cells whose function resembles that of a primitive brain. This brain organ could be used to further our...
Posted On 07 Mar 2014
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Has the cloning of humans become a reality?

On 5 October 2011, the prestigious journal Nature (478; 70-75, 2011) published an article describing the first successful production of a stem-cell line derived from cloned human embryos for use with patients suffering from certain diseases. The first time we heard of the cloning...
Posted On 14 Nov 2013
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