Pulmonary organoids produced from human iPS cells in three dimensions (3D)

Lung organoids have been produced from human pluripotent stem (iPS) cells that contain various components of lung tissue, and even airways and alveolar structures (see HERE). Recapitulation of lung development from human pluripotent stem cells (hPSCs) in three dimensions (3D)...

Legal status of human-animal chimeras – hybrid embryos

In addition to the biomedical and bioethical problems raised by human-animal hybridization, there are also objective legal problems. A recent article in the Journal of Medical Ethics (2014; 40, 284-285) reviewed this topic following a debate in the United Kingdom (UK) House of...

Ten years since the discovery of iPS cells. The current state of their clinical application

  Rev Clin Esp. 2017 Jan – Feb;217(1):30-34. doi: 10.1016/j.rce.2016.08.003. Epub 2016 Oct 5. Justo Aznar Ph.D. MD Julio Tudela Pharm Ph.D. Institute of Life Science – Bioethics Observatory Catholic University of Valencia – Spain iPS cells current clinical...

Stem cell research. The two sides of the coin

Science facing market The “heads” of stem cell research Stem cells today represent a great hope for the future of regenerative medicine due to their ability to differentiate into cell lines of almost any tissue, making them a promising therapeutic option for many...

Intestinal tissue produced from embryonic stem cells and iPS cells

The intestinal nervous system controls several functions of the gastrointestinal tract, and when impaired causes bowel abnormalities. Now, a group of American researchers has generated intestinal tissue from embryonic and iPS cells (this last hasn’t ethics problems), using...

The situation of the clinical use of stem cells

In January 2017, an article was published in JAMA (The Promise of Palliative Care – Translating Clinical Trials to Clinical Care) which, in our opinion, summarises the situation of the clinical use of stem cells extremely well. It begins by referring to the possible sources...

Patient’s own menstrual blood stem cells used to treat Asherman’s syndrome

Infertility treatment.”The best option for endometrial regeneration in patients with Asherman’s syndrome.” Asherman’s syndrome is an acquired uterine abnormality characterised by the presence of intrauterine adhesions, and which clinically causes...

Retinal tissue produced from iPS cells in animals

One of the possible applications of iPS cells is in the treatment of retinal diseases. Now, a group of researchers from the Riken Institute in Kobe (Japan) see HERE has presented some interesting experiments in which they were able to produce retinal tissue from iPS cells (iPS...

Functional artificial eggs obtained for the first time from mouse skin

Scientists in Japan have transformed mouse skin cells into eggs and have managed to obtain fertile offspring after their fertilisation (See Nature article HERE). This study represents the first production of eggs completely in vitro. In 2012, mouse skin cells were reprogrammed...

Cell therapy clinics questioned. Technical and ethical aptitude of clincs in North America

Today in the United States there are 350 cell therapy centres offering stem cell-based treatments for autism, cystic fibrosis, multiple sclerosis and other diseases. Cell therapy clinics questioned because the vast majority lack not only approval by the United States medicines...
12