Ten years since the discovery of iPS cells. The current state of their clinical application

  Rev Clin Esp. 2017 Jan – Feb;217(1):30-34. doi: 10.1016/j.rce.2016.08.003. Epub 2016 Oct 5. Justo Aznar Ph.D. MD Julio Tudela Pharm Ph.D. Institute of Life Science – Bioethics Observatory Catholic University of Valencia – Spain iPS cells current clinical...

Stem cell research. The two sides of the coin

Science facing market The “heads” of stem cell research Stem cells today represent a great hope for the future of regenerative medicine due to their ability to differentiate into cell lines of almost any tissue, making them a promising therapeutic option for many...

The situation of the clinical use of stem cells

In January 2017, an article was published in JAMA (The Promise of Palliative Care – Translating Clinical Trials to Clinical Care) which, in our opinion, summarises the situation of the clinical use of stem cells extremely well. It begins by referring to the possible sources...

Patient’s own menstrual blood stem cells used to treat Asherman’s syndrome

Infertility treatment.”The best option for endometrial regeneration in patients with Asherman’s syndrome.” Asherman’s syndrome is an acquired uterine abnormality characterised by the presence of intrauterine adhesions, and which clinically causes...

New breakthrough in the treatment of Crohn’s disease using cell therapy

Crohn’s disease treatment using cell therapy. In 2009, Spanish researchers (see HERE) proposed the use of mesenchymal stem cells for the treatment of fistulas in Crohn’s disease. The findings of the first phase 3 randomised, double-blind, placebo-controlled clinical...

Functional artificial eggs obtained for the first time from mouse skin

Scientists in Japan have transformed mouse skin cells into eggs and have managed to obtain fertile offspring after their fertilisation (See Nature article HERE). This study represents the first production of eggs completely in vitro. In 2012, mouse skin cells were reprogrammed...

Cell therapy clinics questioned. Technical and ethical aptitude of clincs in North America

Today in the United States there are 350 cell therapy centres offering stem cell-based treatments for autism, cystic fibrosis, multiple sclerosis and other diseases. Cell therapy clinics questioned because the vast majority lack not only approval by the United States medicines...

Potential application of organoids that mimic different organs

In 2011, almost incidentally, Madeline Lancaster of the Institute of Molecular Biotechnology in Vienna managed to produce primitive retina cells and different nerve cells from embryonic stem cells. However, Lancaster and her colleagues were not the first to produce a brain...

Stem cells and the production of organoids at the forefront of biomedical science

There are topics in which biomedical interest merges with ethical interest. One of these is undoubtedly the subject of stem cells wich appears to be the biomedical science forefront. Few issues in the biomedical sciences arouse as much interest as these, and for this reason, the...

What is the current clinical usefulness of stem cell treatments, embryonic and iPS cells?

Human adult stem cells (iPS) have been found to be the most clinically useful human cells for therapeutic purposes Pluripotent cells (iPS) are defined as those from which cells of different tissue types can be obtained. These can be obtained either from preimplantation human...
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