CRISPR used to obtain single-sex offspring in mice

Israeli researchers have used the CRISPR gene-editing tool – read our special report on the issue – to obtain single-sex offspring in mice. In their article published in EMBO reports, the scientists managed to obtain almost exclusively female offspring from the...

China. One step forward the regulation of gene editing in humans

After the birth in China of the first genetically modified humans the result of unregulated experiments, the country has recently introduced a regulation on gene editing in humans. To that end, they have developed a draft of the civil code, by which “experiments on genes in...

CRISPR human experiments. New global registry is proposed and a moratorium in reproductive germline editing

There’s an “urgent need” to create a transparent global registry that would list all experiments related to human genome editing, an expert committee convened to advise the World Health Organization (WHO) said today. The international committee of 18 researchers and bioethicists,...

Human–animal hybrid advisability. Human brain gene introduced into monkeys that seems to increase their intelligence

“Genetic changes should not be introduced in higher animals, as this raises bioethical uncertainties.” Chinese scientists have recently produced transgenic monkeys by introducing a human brain gene into the animals during their embryonic development (produci...

Russian scientist is waiting for the approval of the government to produce babies with a modified genome

Denis Rebrikov, a Russian molecular biologist, has made public his intention to modify the genome of human embryos and then implant them in women to produce genetically modified babies as soon as he can obtain the necessary permits, according to the journal Nature (see HERE)....

Promising experiment with CRISPR. It corrects a lung disease in mouse fetuses but this research still has certain limitations

One step forward in the possibility of applying CRISPR in utero to correct diseases The CRISPR gene editing tool has been applied in utero in mice to correct a mutation that causes a lethal lung disease in mice. These experiments, published recently in Science Translational...

Could CRISPR gene editing tool eradicate entire species? Spanish Institute releases a campaign to eradicate cockroache

Could cockroaches enter in the category of endangered species? Researchers at the Institute of Evolutionary Biology in Barcelona want to use the CRISPR gene editing tool to eradicate cockroaches. The strategy would consist of expanding a harmful genetic trait (sterility) in the...

US authorizes the use of CRISPR directly in the patient’s body, until now the trials was made in cells extracted of the patient

Hopes and and concerns The first clinical trial involving the use of the gene editing tool CRISPR directly in the patient (see more ) has been approved in the United States. The trial aim to treat a congenital blindeness will include around 15 patients, adults and children, in...

Same-sex parents produced in mammals. Mouse pups obtained from “exclusively” male or female pairs

See video below Scientists have managed to produce mouse pups , i.e. bimaternal or bipaternal, in experiments that have been published in Cell Stem Cell. In the aforementioned study, fertile mice were obtained from two females, and mice from two males were born from surrogate...

Legal aspects to take into account in the case of genetically modified babies in China

INTRODUCTION The news has come to light in numerous media: Chinese researcher He Jiankui and his team at SUSTech (Southern University of Science and Technology of China) in Shenzhen have produced the first two genetically-modified human beings using the CRISPR-CAS9 technique...