3D bioprinting for regenerative medicine and to produce organs. State of the art and an ethical reflection

A recent article published in the Journal of Stomatology, Oral and Maxillofacial Surgery (Volume 120, Issue 2, April 2019, Pages 128-132) made a great review with the suggestive title 3D Bioprinting: principles, fantasies and prospects. It is based on a PubMed/MEDLINE search that...

Scientists with 3D – bioink technique print a cornea that mimic human ones. Great hope to patients waiting for cornea donation

Science Daily published an article with the title, 3D printed artificial corneas similar to human ones, we extract the following text, “When a person has a severely damaged cornea, a corneal transplant is required. However, there are 2,000 patients waiting for the cornea...

Promising new treatment of spinal cord injuries presents bioethical problems should be resolved

Spinal cord injuries are one of the pathologies that present the greatest medical issues in regenrative medicine. Thus, their possible treatment with stem cells has meant—and means—one of the major challenges for regenerative and reparatory medicine. Nevertheless, progress in...

Cardiac muscle cells, that drive the beating of the heart, developed from iPS cells

Cardiomyocytes produced with success One of the possibilities for the clinical-experimental use of iPS cells is to develop human-like tissues -organoids- for use in basic research or in preclinical therapeutic studies. Now, using iPS cells obtained from primates, a team from...

Cryopreserve ovarian tissue from prepubertal girls who are to undergo cancer treatment. Medical and ethical approach

When a cancer patient is treated with radio and/or chemotherapy, they can become infertile, both men and women. Consequently, ovarian tissue cryopreservation prior to treatment is recommended in women, with the cryopreserved tissue then transferred again to the patient if she...

Ears made in China, using 3D printing technique, are implanted in 5 children

A team of Chinese scientists has been able to implant ears created using an experimental technology that combines cultured patient’s cells with 3D printing in five children. The children suffered from microtia, a congenital external ear deformity that affects one in every...

Pluripotent stem cells used for regenrative medicine risks. They can develop mutations that favor the production of cancer cells

It should be crucial to check pluripotent cell lines (embryonic and iPS cells) before clinical testing before their use in regenerative medicine The production of pluripotent stem cells, from which virtually all types of cells can be obtained, may be of great use for the...

The future of iPS – induced pluripotent stem cells. New finding increases tremendously their potential for clinical use

Cells now can be obtained from anonymous donors, however, and stored in a cell bank, the costs would be reduced significantly, and their potential for clinical use would increase tremendously A recent article published in Nature discussed some specific aspects regarding the...

3D artificial ovary constructed with excellent results. New hope for women infertility

A team of researchers from the McCormick School of Engineering at Northwestern University in the United States has reported that it has managed to construct the structure of an artificial ovary 3D  (see HERE) a hydrogel that, once transplanted in an animal, can interact with its...

Pulmonary organoids produced from human iPS cells in three dimensions (3D)

Lung organoids have been produced from human pluripotent stem (iPS) cells that contain various components of lung tissue, and even airways and alveolar structures (see HERE). Recapitulation of lung development from human pluripotent stem cells (hPSCs) in three dimensions (3D)...
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