Data from the European Society of Human Reproduction and Embryology (ESHRE) on the use and results of preimplantation genetic diagnosis (PGD) in Europe have been published. The main data included in the report are as follows: The study included 11,130 oocytes collected, 12.8 per stimulation cycle studied. Of these, 62% (6845/11,130) were fertilised and 76% (5176/6845) of the embryos obtained were biopsied. Of the biopsied embryos, a diagnosis was obtained in 94% (4798/5122), of which only 27% (1275/4798) were transferable. Of all the transferable embryos, 70% were transferred and 14% were frozen (Human Reproduction 29; 880-893, 2014).

If we analyse these data in detail, we can see the embryonic manipulation of PGD. In effect, 6845 oocytes were fertilised, from which as many human embryos were obtained. Of these, 5176 were biopsied and 892 were considered transferable, i.e. of the 6845 embryos created, only 892 (13%) were given the opportunity to live (Another matter is whether the embryos transferred resulted in a pregnancy and live birth, but this occurs equally in in-vitro fertilisation techniques in which PGD is not used). Based on the data discussed, it can be concluded that a large number of embryos are lost when subjected to PGD (87%), according to official ESHRE data, something that must be taken into consideration when making an ethical evaluation of this technique.




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