The boy had developed cerebral palsy following a cardiac arrest. When he was a normally developed two-and-a-half-year-old, he suffered global cerebral anoxia that led to a vegetative state. Nine weeks later, he received a transfusion of stem cells from his own umbilical cord blood, which had been preserved at birth. This transfusion was followed by daily active rehabilitation, maintained up to 40 months.

After two months, his muscle movement improved and the spastic paresis was reduced; his electroencephalogram also improved. He was able to recover his smile, sit up and started to babble a few words. At 40 months he ate independently and his speech improved.

This functional neuroregeneration is difficult to explain by rehabilitation alone, and suggests that umbilical cord blood stem cell transplant could have contributed to the clinical improvement obtained after the paralysis secondary to global ischaemic brain damage (Hindawi Publishing Corporation. Case Reports in Transplantation, 2013, Article ID 951-827, 6 pages.




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