“The increased risk was 2-fold higher for children conceived via in vitro fertilization than for children conceived naturally.”

An article published in JAMA Network Open (read HERE)  evaluates some adverse side effects that children conceived via in vitro fertilization may develop. In this respect, our Observatory has published several articles Read HERE and HERE. Our main concern is if the couple that is opting for IVF techniques has adequate information to do their consent.


IVF children defects  related to childhood cancer is studied


The extensive American study published last October included 1,000,639 children conceived naturally as a control group, and 52,776 children conceived via in vitro fertilization, between 2004 and 2016 in Massachusetts and North Carolina, and between 2004 and 2013 in Texas. The children were followed up for a period of 5.7 years.

Differences of incidence in children birth defects between IVF children and children conceived naturally

The article states that in children with birth defects conceived naturally, the risk of cancer (in the time period evaluated) was 3.15 times higher than that of children without birth defects conceived naturally; however, in those conceived by in vitro fertilization, the risk was 6.9 times higher. The extensive study concluded, “The increased risk was 2-fold higher for children conceived via in vitro fertilization than for children conceived naturally.” Our opinion is that more of this kind of study with a longer follow-up is needed.