A group of scientists from the University of Southern California has developed a method to continuously produce progenitor cells capable of generating macrophages, a type of cell essential for the functioning of the immune system. In a study published in [...]
The history of human progress is inextricably linked to scientific knowledge and technological development. Today, at the dawn of a new era marked by artificial intelligence (AI), gene editing and nuclear fusion, mankind is facing an unprecedented promise of well-being [...]
Faced with the urgent challenge of eradicating global hunger and finding sustainable alternatives to meat, the latest generation of genetic engineering offers a revolutionary solution. Using CRISPR-Cas9 technology, scientists have managed to optimize the fungus Fusarium venenatum by eliminating specific [...]
A new scientific study published in The New England Journal of Medicine has revealed promising results in the treatment of CPS1 enzyme deficiency, one of the most serious and rare urea cycle disorders. The congenital condition, with an estimated incidence [...]
CRISPR-based gene therapy represents one of the most promising frontiers of precision medicine, especially in the treatment of mitochondrial diseases, hitherto considered incurable. This article by Nicolás Jouve analyses the latest scientific advances that have made it possible to overcome [...]
Since its inception in the 1980s, genetic engineering has evolved to become a high-precision tool in medicine. The advent of technologies such as CRISPR-Cas9 and its advancement towards systems such as prime editing and the recently developed bridge recombination has unlocked an unprecedented [...]
A theoretical analysis by Australian authors and the newly created Uehiro Institute in Oxford has just been published in Nature, which we consider merits special attention. The article discusses gene editing in germ (gamete-generating) cells or human embryos using the CRISPR-Cas9 technique [1]. [...]
For the first time, a Spanish trial developed over 20 years has succeeded in curing Fanconi anemia patients with gene therapy. Fanconi anemia is a rare genetic disorder affecting bone marrow, characterized by impaired DNA repair mechanisms, causing a progressive loss [...]
Gene editing is far from being a safe technique today, because not all modifications that occur in the genome after its application are desired, leading to genetic changes with unpredictable consequences. Furthermore, due to the limited knowledge of how our [...]
A recent article published in Cell presents the case of a woman with type 1 diabetes who, after receiving a transplant of reprogrammed induced pluripotent stem cells, has managed to produce her own insulin. The operation, performed in June 2023, [...]
Scientists from University College London (United Kingdom) have published research in Nature Medicine in which fetal stem/progenitor cells were obtained from amniotic fluid and grown in the laboratory to give rise to organoids. These are three-dimensional models of miniature organs [...]
The major breakthroughs in genetic engineering took place in the 1960s and 1980s, and from these developments emerged the technologies that would allow the isolation, cloning and artificial transfer of genes from one individual to another, even between different species, [...]
