A recent study in Fertility and Sterility (Fertil Steril, 101; 1321-1325, 2014) that included 106,666 children born through in-vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI) between 2000 and 2010 in the United Kingdom found a tendency for more boys to be born than girls, especially when IVF is used. At present, 2%-3% of children in the UK are born through these techniques, so “it is not likely that a gender bias within that proportion will be a cause for concern. However, the impact of deviation in SSR [secondary sex ratio] should be considered for the future if the proportion of ART births in human populations continues to rise”.


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