A 3D bioprinted organoid that mimics an animal heart has been produced using human iPS cells, as published in Circulation Research on 3 July 2020. The encouraging news is that six weeks after producing it, it was able to beat. In the authors’ view, the production of this organoid represents a crucial step toward the possibility of generating more complex human tissues that could be used to test artificial hearts, and even as a therapeutic possibility in human medicine (see more HERE).
This 3D bioprinted heart achievement represents an advancement in relation to other experiences
The researchers say “While multiple groups have generated variations on tissue-engineered ventricles and whole heart models, the hChaMP is the first to achieve robust electromechanical function in a perfusable, chambered cardiac pump. Notably, we show that the hChaMP can maintain these functions for at least 6 weeks, while most similar models of 3D bioprinted heart have been characterized only up to 2 weeks after fabrication.” The great achievement is to maintain the complex electromechanical function of the new organoid. It is a step forward to produce organic hearts to replace heart devices. It is news of hope to the patient that faces the shortage of organ for transplant and persons with severe heart dysfunctions. The use of iPS cells in this experimentation makes that it has no bioethical problems.