Cardiomyocytes produced with success
One of the possibilities for the clinical-experimental use of iPS cells is to develop human-like tissues -organoids- for use in basic research or in preclinical therapeutic studies. Now, using iPS cells obtained from primates, a team from Colombia University in New York has produced cardiomyocytes (heart muscle cells capable of contracting spontaneously and individually) with >85% purity in only 10 days in the presence of a biochemical medium, in very defined conditions. 85% The cells obtained showed normal cardiac markers and electromechanical characteristics. They say “Our approach provides a powerful tool for the generation of NHP iPSC-derived cardiomyocytes amenable to utilization in basic research and preclinical studies, including in vivo tissue regeneration models and drug screening (see HERE article).
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